Phytochemical Screening, and Antibacterial and Antioxidant Activities of Mangifera indica L. Leaves

The bio-constituents of medicinal plants are greatly influenced by the environmental conditions and growing seasons. This study aimed to uncover presence different metabolites investigate biological properties leaves Mangifera indica during summer winter extract M. for using solvent extracts (hexane, chloroform, methanol) showed phenols, flavonoids, tannins, terpenoids, alkaloids, phytosterol, saponins, steroids, carbohydrates. Antibacterial activity methanolic leaf were evaluated against bacterial species Staphylococcus aureus (ATCC 43300) Escherichia coli 25922). For S. (ATTC 43300), crude displayed lower antibacterial than control streptomycin, with zones inhibition 14.17 16.67 mm, respectively. Winter had a zone 12 while streptomycin 13.67 mm inhibition. E. 25922), higher gentamycin, 18.05 17.5 8.5 gentamycin 14.5 screening positive results both seasons; however, more potent effect. antioxidant was conducted 2,2-diphenyl-1-picryl hydrazyl radical (DPPH) assay. Potent scavenging exhibited seasons hexane (IC50 19.53 μg/mL 12.71 μg/mL, respectively) (22.32 14.35 in comparison ascorbic acid, which produced an IC50 3.20 μg/mL. better capacity extracts. In conclusion, significant activity, activity. Further studies required strains bacteria cancer cell lines test potency.